January 2016 Science Bulletin: Organophosphate pesticides reduce child lung function; small particulates raise embolism risk; and more

January 17, 2016 at 4:51 pm | Posted in News and Science Bulletins | Leave a comment

January 2016 Science Bulletin

Pesticides, risk assessment | Pesticide authorization in the EU-environment unprotected? Is there something amiss with risk assessment and regulatory enforcement? This meta-analysis finds that in 45% of cases (n=1566), measured insecticide concentrations in EU surface waters exceeded the regulatory acceptable limit as determined by risk assessment.

Pesticides, lung function (human) | Decreased lung function in 7-year-old children with early-life organophosphate exposure. This study presents the first scientific evidence that non-occupational early-life exposure to OPs (ie, chronic low-level exposure to OPs at environmental relevant concentrations) is associated with decreased pulmonary function and may have a restrictive effect on children’s lungs.

Air pollution, cardiovascular disease (human) | Prospective Study of Ambient Particulate Matter Exposure and Risk of Pulmonary Embolism in the Nurses’ Health Study Cohort. PM2.5 averaged over 1 month (HR = 1.22; 95% CI: 1.04, 1.44) or 12 months (HR = 1.17; 95% CI: 0.93, 1.48) was associated with incident PE, after adjusting for known risk factors and PM2.5-10. Equivalent analyses restricted to PE subtypes showed a positive association for PM2.5 with nonidiopathic PE, but not with idiopathic PE. We did not find evidence of an association between distance to roadways and PE risk.

Organophosphate flame retardants, exposure (human) | High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products. The number of infant products owned was strongly associated with BDCIPP; children with >16 products had tris(1,3-dichloro-2-propyl)phosphate metabolite BDCIPP levels that were 6.8 times those with <13 (p = 0.02). Infants attending daycare centers also had higher BDCIPP levels (3.7 times those of others; p = 0.07), suggesting time spent in this microenvironment contributes to higher exposure.

Green chemistry | Review of the twenty-three year evolution of the first university course in green chemistry: teaching future leaders how to create sustainable societies. How to teach green chemistry; and how to get universities to run green chemistry courses.

PFCs, endocrine disruption (human) | Prenatal Exposure to Perfluoroalkyl Acids and Serum Testosterone Concentrations at 15 Years of Age in Female ALSPAC Study Participants. Adjusted total testosterone concentrations were on average 0.18-nmol/L (95% CI: 0.01, 0.35) higher in daughters with prenatal PFOS in the upper concentration tertile compared with daughters with prenatal PFOS in the lower tertile. Adjusted total testosterone concentrations were also higher in daughters with prenatal concentrations of PFOA (β = 0.24; 95% CI: 0.05, 0.43) and PFHxS (β = 0.18; 95% CI: 0.00, 0.35) in the upper tertile compared with daughters with concentrations in the lower tertile.

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