May 2014 Science Digest #1: Recent human research

May 22, 2014 at 1:35 pm | Posted in News and Science Bulletins | Leave a comment

BPA, Obesity | Urinary concentrations of bisphenol a and phthalate metabolites and weight change: a prospective investigation in US women. Examination of longitudinal associations between endocrine disruptor exposure levels and body weight changes. The results suggest urinary concentrations of BPA and certain individual phthalate metabolites were associated with modest weight gain in a dose-dependent manner.

Pesticides, Exposure | Reduction in urinary organophosphate pesticide metabolites in adults after a week-long organic diet. Organophosphate pesticide exposure in Australian adults is mainly through the diet. One week of eating mostly organic food reduced urine pesticide levels by nearly 90%. The clinical relevance of reducing pesticide exposure requires further study. Eating organic food is a precautionary approach to reduce pesticide exposure.

Pesticides, Diabetes | Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study. Results here are consistent with previous studies reporting an association between specific organochlorines and diabetes and add to growing evidence that certain organophosphates also may increase risk.

BPA, Miscarriage | Conjugated bisphenol A (BPA) in maternal serum in relation to miscarriage risk. Maternal conjugated BPA was associated with a higher risk of aneuploid and euploid miscarriage in this cohort. The impact of reducing individual exposure on future pregnancy outcomes deserves further study.

Fire retardants, Exposure | A systematic review of the human body burden of e-waste exposure in China. These results suggest that residents in the e-waste exposure areas, located mainly in the three traditional e-waste recycling sites (Taizhou, Guiyu, and Qingyuan), are faced with a potential higher daily intake of these pollutants than residents in the control areas, especially via food ingestion. Moreover, pollutants (PBBs, PBDEs, PCBs, PCDD/Fs, and heavy metals) from the e-waste recycling processes were all detectable in the tissue samples at high levels, showing that they had entered residents’ bodies through the environment and dietary exposure.

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