Feb 2014 science digest #1: recent epidemiological research

February 6, 2014 at 2:20 pm | Posted in News and Science Bulletins | Leave a comment

PCBs, Obesity | Association between prenatal polychlorinated biphenyl exposure and obesity development at ages 5 and 7 y: a prospective cohort study of 656 children from the Faroe Islands. Am J Clin Nutr: These results suggest that prenatal exposure to PCB and DDE may play a role for subsequent obesity development. Girls whose mothers have a high prepregnancy BMI seem most affected.

Organophosphates, Parkinson’s Disease | The association between ambient exposure to organophosphates and Parkinson’s disease risk. This study adds to evidence that OPs are implicated in the aetiology of idiopathic PD. However, studies of OPs at low doses reflective of real-world ambient exposure are needed to determine the mechanisms of neurotoxicity.

POPs, Asthma | Maternal Concentrations of Persistent Organochlorine Pollutants and the Risk of Asthma in Offspring: Results from a Prospective Cohort with 20 Years of Follow-up. Maternal concentrations of PCB-118 and HCB were associated with increased risk of asthma in offspring followed through to 20 years of age.

PCBs, Cognition | Polychlorinated Biphenyl Exposures and Cognition in Older U.S. Adults: NHANES (1999–2002). These findings support the hypothesis that PCB exposure has adverse cognitive effects even at levels generally considered to pose low or no risk, perhaps affecting mainly those of advanced age.

Dioxin, Bone Density | Serum Dioxin Concentrations and Bone Density and Structure in the Seveso Women’s Health Study. These results do not support the hypothesis that postnatal TCDD exposure adversely affects adult bone health. Continued follow-up of Seveso women who were youngest at exposure is warranted. Future studies should also focus on those exposed in utero.

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