Research digest #2 (Oct 2013). Recent peer-reviewed research into chemical toxicity (non-human), risk assessment and risk management

October 19, 2013 at 10:59 am | Posted in News and Science Bulletins | Leave a comment

Perinatally Administered Bisphenol A as a Potential Mammary Gland Carcinogen in Rats. These findings suggest that developmental exposure to environmentally relevant levels of BPA during gestation and lactation induces mammary gland neoplasms in the absence of any additional carcinogenic treatment. Thus, BPA may act as a complete mammary gland carcinogen. (Study synopsis here.)

EDCs: negotiating the precautionary principle. LANCET (Diab & Endo): Few scientific issues are more complex or controversial than assessment of the effects of endocrine-disrupting chemicals (EDCs) on human wellbeing. Several scientific disciplines are involved—including toxicology, endocrinology, environmental science, paediatrics, obstetrics and gynaecology, and public health—each with different questions and priorities.

Policy Decisions on Endocrine Disruptors Should Be Based on Science Across Disciplines: A Response to Dietrich et al. “We are writing as scientists and editors of leading peer-reviewed journals that have published important contributions in the study of endocrine disrupting chemicals (EDCs). By signing this editorial, we affirm that regulatory decisions on EDCs should be made based on the best available science and expertise that involves, among others, reproductive biology, endocrinology, medicine, genetics, behavior, developmental biology and toxicology.”

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