5&5: News and Science Highlights from February 2012

March 7, 2012 at 8:46 pm | Posted in Uncategorized | Leave a comment


“Probable link” between pregnancy-induced hypertension and PFOA contamination. Explanation of one of the legal “probable-cause” findings which are the scientific basis of determination of DuPont’s liabilities with regard to contaminating a waterway with PFOA.

Obesogens: an environmental link to obesity. Accessible and comprehensive EHP cover feature looking at the mechanisms of action and potential culprits in the obesogen hypothesis.

Cashew nut pesticide linked to blood cancers in Indian children. Report on how a widely-banned pesticide, still extensively used in cashew nut and other cash crop plantations in developing countries, has been found in the bone marrow of children suffering from blood cancers in the areas using the pesticide.

Long-awaited dioxins report released; EPA says low doses risky but most people safe. After 21 years of wrangling over health threats, uncertain science and industry pressure, the U.S. Environmental Protection Agency on Friday released its health assessment of dioxins, concluding there are potentially serious effects even at very low levels of exposure.

Call for new approach on endocrine disruptors. The final version of an EU-commissioned report recommends EDCs be treated as a distinct regulatory category (as for CMRs and PBTs), and cautions that existing, internationally-agreed and validated test protocols capture only a limited range of potential ED effects.


Urinary Bisphenol: A Concentration and Risk of Future Coronary Artery Disease in Apparently Healthy Men and Women. The associations found here between higher BPA exposure and incident CAD show similar trends to cross-sectional findings in the more highly exposed NHANES respondents. Study sponsored by the British Heart Foundation and published in the Journal of the American Heart Association.

Prenatal Exposure to PFOA and Risk of Overweight at 20 Years of Age. Propsective study replicating in humans findings in mice that PFOA exposure increases weight gain and adiposity, with women gestationally exposed to PFOA more likely to be obese at 20 years.

Solvent exposures and Parkinson Disease risk in twins. US epidemiological research finding that exposure to trichloroethylene, the most common organic contaminant in US groundwater, and PERC and CCl4 (also ubiquitous in the environment) may increase risk of PD.

Concentrations and speciation of polybrominated diphenyl ethers in human amniotic fluid. Although PBDE accumulation in humans has been noted since the 1970s, this is the first to date which identifies levels in amniotic fluid. PBDE congeners were identified in all samples.

Birth Weight and Prenatal Exposure to PCBs and DDE: A Meta-analysis within 12 European Birth Cohorts. Low-level exposure to PCB (or correlated exposures) impairs fetal growth, suggests this large meta-analysis, with the effects of PCB 153 exposure on birth weight equivalent to the effects of a pregnant mother smoking 10 cigarettes a day.

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